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Comparison of the Complior Analyse device with Sphygmocor and Complior SP for pulse wave velocity and central pressure assessment

Stea, Francesco and Bozec, Erwan and Millasseau, Sandrine and Khettab, Hakim and Boutouyrie, Pierre and Laurent, Stéphane (2014) Comparison of the Complior Analyse device with Sphygmocor and Complior SP for pulse wave velocity and central pressure assessment. Journal of Hypertension, 32 (4). pp. 873-880. ISSN 0263-6352

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    BACKGROUND: The Complior device (Alam Medical, France) was used in epidemiological studies which established pulse wave velocity (PWV) as a cardiovascular risk marker. Central pressure is related, but complementary to PWV and also associated to cardiovascular outcomes. The new Complior Analyse measures both PWV and central blood pressure during the same acquisition. The aim of this study was to compare PWV values from Complior Analyse with the previous Complior SP (PWVcs) and with Sphygmocor (PWVscr; AtCor, Australia), and to compare central systolic pressure from Complior Analyse and Sphygmocor. METHOD: Peripheral and central pressures and PWV were measured with the three devices in 112 patients. PWV measurements from Complior Analyse were analysed using two foot-detection algorithms (PWVca_it and PWVca_cs). Both radial (ao-SBPscr) and carotid (car-SBPscr) approaches from Sphygmocor were compared to carotid Complior Analyse measurements (car-SBPca). The same distance and same calibrating pressures were used for all devices. RESULTS: PWVca_it was strongly correlated to PWVscr (R(2) = 0.93, P < 0.001) with a difference of 0.0 ± 0.7 m/s. PWVca_cs was also correlated to PWVcs (R(2) = 0.90, P < 0.001) with a difference of 0.1 ± 0.7 m/s. Central systolic pressures were strongly correlated. The difference between car-SBPca and ao-SBPscr was 3.1 ± 4.2 mmHg (P < 0.001), statistically equivalent to the difference between car-SBPscr and ao-SBPscr (3.9 ± 5.8 mmHg, P < 0.001), whilst the difference between car-SBPca and car-SBPscr was negligible (-0.7 ± 5.6 mmHg, P = NS). CONCLUSION: The new Complior Analyse device provides equivalent results for PWV and central pressure values to the Sphygmocor and Complior SP. It reaches Association for the Advancement of Medical Instrumentation standard for central blood pressure and grades as excellent for PWV on the Artery Society criteria. It can be interchanged with existing devices.

    Item Type: Article
    Additional Information: Accepted manuscript
    Subjects: Area06 - Scienze mediche > MED/11 - Malattie dell'apparato cardiovascolare
    Depositing User: Dr. Francesco Stea
    Date Deposited: 06 Mar 2015 14:29
    Last Modified: 06 Mar 2015 14:29
    URI: http://eprints.adm.unipi.it/id/eprint/2322

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