2024-03-29T14:12:14Z
http://eprints.adm.unipi.it/cgi/oai2
oai:eprints.adm.unipi.it:12
2010-12-20T10:44:35Z
oai:eprints.adm.unipi.it:449
2010-12-20T10:57:54Z
7374617475733D707562
7375626A656374733D417265613033:4348494D2F3033
74797065733D61727469636C65
http://eprints.adm.unipi.it/449/
Stefano Guerri: un esemplare curriculum di studi da farmacista
Lùperi, Patrizia
CHIM/03 - Chimica generale e inorganica
RIASSUNTO Nell'articolo si prendono in considerazione, oltre alla carriera studentesca e professionale del protagonista, anche gli insegnamenti in corso presso l'Università in un periodo di grande fervore, come quello di fine ottocento. SUMMARY In the article we analize, as well as Stefano Guerri's studies and career, history of the University of Pisa in a so historically interesting ad important period as the last quarter of XIX century.
1998-06
Article
NonPeerReviewed
application/pdf
it
http://eprints.adm.unipi.it/449/1/articolo_S._Guerri.pdf
Lùperi, Patrizia (1998) Stefano Guerri: un esemplare curriculum di studi da farmacista. NCF, Notiziario Chimico Farmaceutico, 1998 (5). pp. 118-120. ISSN 0393-3733
oai:eprints.adm.unipi.it:528
2010-12-20T10:54:20Z
7374617475733D707562
7375626A656374733D417265613033:4348494D2F3036
7375626A656374733D417265613033:4348494D2F3032
74797065733D61727469636C65
http://eprints.adm.unipi.it/528/
Stereochemistry of atropisomeric 9,10-dihydrophenanthrene dimers from Pholidota chinensis
Yao, Sheng
Tang, Chun-Ping
Ye, Yang
Kurtán, Tibor
Kiss-Szikszai, Attila
Antus, Sándor
Pescitelli, Gennaro
Salvadori, Piero
Krohn, Karsten
CHIM/06 - Chimica organica
CHIM/02 - Chimica fisica
Six bis-9,10-dihydrophenanthrene and 9,10-dihydrophenanthrene/(dihydro)stilbene derivatives, phochinenins G-L (1-6), were isolated from the whole plant of Pholidota chinensis. Their structures were elucidated on the basis of extensive spectroscopic investigations (1D, 2D NMR and HR-EIMS). Owing to the sterically hindered rotation around the biaryl axis, some of these biaryl compounds can exist as a pair of enantiomers, but were isolated as racemates. Computed inversion barriers of selected atropisomeric derivatives suggested that phochinenins K (5), gymconpin C (7) and flavanthrin (9) have optically stable atropisomers. Their racemates were separated by HPLC on an optically active stationary phase, and stereochemically characterized on-line by circular dichroism (CD) spectroscopy (LC-CD coupling), in conjunction with quantum-mechanics CD calculations.
2008-08-18
Article
PeerReviewed
application/pdf
it
http://eprints.adm.unipi.it/528/1/Pholidota_dihydrophenanthrenes.pdf
Yao, Sheng and Tang, Chun-Ping and Ye, Yang and Kurtán, Tibor and Kiss-Szikszai, Attila and Antus, Sándor and Pescitelli, Gennaro and Salvadori, Piero and Krohn, Karsten (2008) Stereochemistry of atropisomeric 9,10-dihydrophenanthrene dimers from Pholidota chinensis. Tetrahedron Asymmetry, 2008 (19). pp. 2007-2014. ISSN 0957-4166
http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6THT-4TDVR87-5&_user=793840&_rdoc=1&_fmt=&_orig=search&_sort=d&view=c&_acct=C000043460&_version=1&_urlVersion=0&_userid=793840&md5=9f2979e932a81a62237d9105079d7e37
10.1016/j.tetasy.2008.08.013
oai:eprints.adm.unipi.it:580
2010-12-20T11:25:47Z
oai:eprints.adm.unipi.it:582
2010-12-20T10:52:22Z
7374617475733D707562
7375626A656374733D417265613033:4348494D2F3036
74797065733D61727469636C65
http://eprints.adm.unipi.it/582/
Toward the synthesis of fine chemicals from lactose: preparation of d-xylo and l-lyxo-aldohexos-5-ulose derivatives
Catelani, Giorgio
D’Andrea, Felicia
Guazzelli, Lorenzo
Pistarà, Venerando
CHIM/06 - Chimica organica
SUMMARY The transformation of (5R)-2,6-di-O-benzyl-5-C-methoxy-β-d-galactopyranosyl-(1→4)-2,3:5,6-di-O-isopropylidene-aldehydo-d-glucose dimethyl acetal (8) into partially protected derivatives of d-xylo- and l-lyxo-aldohexos-5-ulose has been reported, applying appropriate epimerisation methods to its 3′-O- and 4′-O-protected alcoholic derivatives.
2009-04-21
Article
PeerReviewed
application/pdf
it
http://eprints.adm.unipi.it/582/1/Manuscrip__Carb.Res_2009__344__717a724.pdf
Catelani, Giorgio and D’Andrea, Felicia and Guazzelli, Lorenzo and Pistarà, Venerando (2009) Toward the synthesis of fine chemicals from lactose: preparation of d-xylo and l-lyxo-aldohexos-5-ulose derivatives. Carbohydrate Research, 344/20 (6). pp. 717-724. ISSN 0008-6215
http://www.sciencedirect.com/science/journal/00086215
doi:10.1016/j.carres.2009.01.014
oai:eprints.adm.unipi.it:591
2010-12-20T10:52:37Z
7374617475733D707562
7375626A656374733D417265613033:4348494D2F3036
74797065733D61727469636C65
http://eprints.adm.unipi.it/591/
Stereoselective entry into the D-GalNAc series starting from the D-Gal one: a new access to N-acetyl-D-galactosamine and derivatives thereof
Guazzelli, Lorenzo
Catelani, Giorgio
D'Andrea, Felicia
Giannarelli, Alessia
CHIM/06 - Chimica organica
A new stereoselective preparation of N-aceyl-D-galactosamine (1b) starting from the known p-methoxyphenyl 3,4-O-isopropylidene-6-O-(1-methoxy-1-methylethyl)-b-D-galactopyranoside (10) is described using a simple strategy based on (a) epimerization at C-2 of 10 via oxidation–reduction to give the talo derivative 11, (b) amination with configurational inversion at C-2 of 11 via a SN2-type reaction on its 2- imidazylate, (c) anomeric deprotection of the p-methoxyphenyl beta-D-galactosamine glycoside 14, (d) complete deprotection. Applying the same protocol to 2,3:5,6:30,40-tri-O-isopropylidene-60-O-(1-methoxy- 1-methylethyl)-lactose dimethyl acetal (4), directly obtained through acetonation of lactose, the disaccharide beta-D-GalNAcp-(1?4)-D-Glcp (1a) was obtained with complete stereoselectivity in good (40%) overall yield from lactose.
2009-02-17
Article
PeerReviewed
application/pdf
it
http://eprints.adm.unipi.it/591/1/CarRes_GalNAc.pdf
Guazzelli, Lorenzo and Catelani, Giorgio and D'Andrea, Felicia and Giannarelli, Alessia (2009) Stereoselective entry into the D-GalNAc series starting from the D-Gal one: a new access to N-acetyl-D-galactosamine and derivatives thereof. Carbohydrate Research, 344/20 (3). pp. 298-303. ISSN 0008-6215
http://www.sciencedirect.com/science/journal/00086215
doi:10.1016/j.carres.2008.11.018
oai:eprints.adm.unipi.it:592
2010-12-20T10:52:33Z
7374617475733D707562
7375626A656374733D417265613033:4348494D2F3036
74797065733D61727469636C65
http://eprints.adm.unipi.it/592/
Synthesis of glycose carbamides and evaluation of the induction of erythroid differentiation of human erythroleukemic K562 cells
Landi, Martina
Catelani, Giorgio
D’Andrea, Felicia
Ghidini, Eleonora
Amari, Gabriele
Puccini, Paola
Bianchi, Nicoletta
Gambari, Roberto
CHIM/06 - Chimica organica
SUMMARY A series of carbamides derived from 1,2:5,6-di-O-isopropylidene-D-gluco- (1) and D-allofuranose (3) as well as their 5,6-O-deprotected analogues (2 and 4) and methyl 3,4-O-isopropylidene-alfa- and beta-D-galactopyranosides (5 and 6) have been prepared in order to evaluate their ability to induce erythroid differentiation of human erythroleukemic K562 cells. Twenty out of 51 carbamides tested exhibit an appreciable activity as inducers of erythroid differentiation and have been fully characterized and described.
2009-02
Article
NonPeerReviewed
application/pdf
it
http://eprints.adm.unipi.it/592/1/Amides_for_UniEprint.pdf
Landi, Martina and Catelani, Giorgio and D’Andrea, Felicia and Ghidini, Eleonora and Amari, Gabriele and Puccini, Paola and Bianchi, Nicoletta and Gambari, Roberto (2009) Synthesis of glycose carbamides and evaluation of the induction of erythroid differentiation of human erythroleukemic K562 cells. European Journal of Medicinal Chemistry, 44 (2). pp. 745-754. ISSN 0223-5234
http://www.sciencedirect.com/science/journal/02235234
doi:10.1016/j.ejmech.2008.05.001
oai:eprints.adm.unipi.it:595
2010-12-20T10:51:52Z
7374617475733D707562
7375626A656374733D417265613033:4348494D2F3036
74797065733D61727469636C65
http://eprints.adm.unipi.it/595/
A new stereoselective approach to a selectively protected derivative of D-pinitol and its evaluation as a-L-rhamnopyranose mimetic
Catelani, Giorgio
D'Andrea, Felicia
Griselli, Alessio
Toma, Lucio
Guazzelli, Lorenzo
Legnani, Laura
CHIM/06 - Chimica organica
SUMMARY The synthesis of 3,5-di-O-benzyl-D-pinitol has been stereoselectively accomplished through intramolecular aldolization of 2,6-di-O-benzyl-4-O-methyl-L-lyxo-hexos-5-ulose followed by reduction with NaBH( OAc)3. Computational analysis [DFT calculations at the B3LYP/6-31G(d) level] suggests that D-pinitol in water largely prefers the conformation corresponding to the 1C4 one of a a-L-rhamnopyranoside unit, being thus a good candidate for its mimicking.
2008-07-21
Article
PeerReviewed
application/pdf
it
http://eprints.adm.unipi.it/595/1/MS_pinitol_for_UniEprint.pdf
Catelani, Giorgio and D'Andrea, Felicia and Griselli, Alessio and Toma, Lucio and Guazzelli, Lorenzo and Legnani, Laura (2008) A new stereoselective approach to a selectively protected derivative of D-pinitol and its evaluation as a-L-rhamnopyranose mimetic. Tetrahedron Letters, 49 (29-30). pp. 4534-4536. ISSN 0040-4039
http://www.sciencedirect.com/science/journal/00404039
doi:10.1016/j.tetlet.2008.05.040
oai:eprints.adm.unipi.it:619
2010-12-20T10:50:21Z
7374617475733D707562
7375626A656374733D417265613033:4348494D2F3036
74797065733D61727469636C65
http://eprints.adm.unipi.it/619/
A new route for the synthesis of Streptococcus pneumoniae 19F and 19A capsular polysaccharide fragments avoiding the beta-mannosamine glycosylation step
Bonaccorsi, Filippo
Catelani, Giorgio
Oscarson, Stephan
CHIM/06 - Chimica organica
SUMMARY The recently described (Carbohydr. Res. 2008, 43, 2545-2556) b-D-MaNAcp- (1→4)-b-D-Glcp thiophenyl glycosyl donor 3 was used in a-glycosylation reactions of OH-2 and OH-3 of the suitably protected p-MeO-benzyl a-L-rhamnopyranoside acceptors 7 and 8. The glycosylation of axial OH-2 of 7 took place in high yield (76%) and with good stereoselectivity (a/b = 3.4) leading to the protected trisaccharide a-11, corresponding to the repeating unit of Streptococcus pneumoniae 19F. The same reaction on equatorial OH-3 of acceptor 8 gave the trisaccharide a-15, constituent of the repeating unit of S. pneumoniae 19A, but in lower yield (41%) and without stereoselection (a/b = 1:1.3). Utilizing the introduced orthogonal protection of OH-1 and OH-4’’, the trisaccharide a-11 was transformed into a trisaccharide building block suitable for the synthesis of its phosphorylated oligomers.
2009-08-17
Article
PeerReviewed
application/pdf
it
http://eprints.adm.unipi.it/619/1/ManuscriptSP19.pdf
Bonaccorsi, Filippo and Catelani, Giorgio and Oscarson, Stephan (2009) A new route for the synthesis of Streptococcus pneumoniae 19F and 19A capsular polysaccharide fragments avoiding the beta-mannosamine glycosylation step. Carbohydrate Research, 344 (12). pp. 1442-1448. ISSN 0008-6215
http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6TFF-4W38RKB-2&_user=793840&_rdoc=1&_fmt=&_orig=search&_sort=d&_docanchor=&view=c&_acct=C000043460&_version=1&_urlVersion=0&_userid=793840&md5=e76a0f5ab582dd71015730a7ee2bb24f
doi:10.1016/j.carres.2009.04.012
oai:eprints.adm.unipi.it:634
2010-12-20T10:49:14Z
7374617475733D707562
7375626A656374733D417265613033:4348494D2F3036
74797065733D61727469636C65
http://eprints.adm.unipi.it/634/
Lactose as an inexpensive starting material for the preparation of aldohexos-5-uloses: synthesis of L-ribo and D-lyxo derivatives
Catelani, Giorgio
Guazzelli, Lorenzo
D'Andrea, Felicia
CHIM/06 - Chimica organica
SUMMARY: Partially protected derivatives of L-ribo- and D-lyxo-aldohexos-5-ulose have been prepared starting from triacetonlactose dimethyl acetal derivatives. Key steps of the synthetic sequences are a) the synthesis of 4'-deoxy-4'-eno- and 6'-deoxy-5'-eno lactose derivatives, and b) the epoxidation-methanolysis of the above enol ethers to give 1,5-bis-glycopyranosides, masked form of the target 1,5-dicarbonyl hexoses.
2010-02-11
Article
PeerReviewed
application/pdf
it
http://eprints.adm.unipi.it/634/1/carbres_2010_369.pdf
Catelani, Giorgio and Guazzelli, Lorenzo and D'Andrea, Felicia (2010) Lactose as an inexpensive starting material for the preparation of aldohexos-5-uloses: synthesis of L-ribo and D-lyxo derivatives. Carbohydrate Research, 345/20 (3). pp. 369-376. ISSN 0008-6215
http://www.sciencedirect.com/science/journal/00086215
doi:10.1016/j.carres.2009.11.027
oai:eprints.adm.unipi.it:637
2010-12-20T11:24:47Z
oai:eprints.adm.unipi.it:638
2010-12-20T11:24:21Z
oai:eprints.adm.unipi.it:639
2010-12-20T11:24:20Z
oai:eprints.adm.unipi.it:640
2010-12-20T11:24:30Z
oai:eprints.adm.unipi.it:641
2010-12-20T11:24:34Z
oai:eprints.adm.unipi.it:642
2010-12-20T11:24:10Z
oai:eprints.adm.unipi.it:646
2010-12-20T10:49:03Z
7374617475733D707562
7375626A656374733D417265613035:42494F2F3034
7375626A656374733D417265613037:4147522F3034
7375626A656374733D417265613033:4348494D2F3038
74797065733D61727469636C65
http://eprints.adm.unipi.it/646/
Establishment of in vitro tissue cultures from Echinacea angustifolia D.C. adult plants for the production of phytochemical compounds
Lucchesini, Mariella
Bertoli, Alessandra
Mensuali-Sodi, Anna
Pistelli, Luisa
BIO/04 - Fisiologia vegetale
AGR/04 - Orticoltura e floricoltura
CHIM/08 - Chimica farmaceutica
SUMMARY The establishment of in vitro cultures of Echinacea angustifolia D.C. was obtained directly from sections of flower stalks of adult plants. The shoot formation was obtained from this plantmaterial placed on a modified MS basal medium named CH supplemented with 0.5 mg L1 6 benzylaminopurine (BA). The in vitro propagation procedure of E. angustifolia consisted of three distinct phases: an initial regeneration phase fromstalk sections (IP shoots on basal mediumwith 0.25 mg L1 BA), an elongation phase on active charcoal and an axillary proliferation of the shoots (AP shoots on basal medium with 0.5 mg L1 BA).Regenerating calli were established from leaves of in vitro shoots cultured on CH medium supplemented with 3 mg L1 BA and 0.5 mg L1 indole-3-butyric acid (IBA). Developed shoots from the callus cultures were subcultured on the CH medium with 0.5 mg L1 BA (leaf regenerated shoots: LR shoots). The secondary metabolite content of the in vitro plant material was compared with that of the greenhouse growing plants. The quali-quantitative LC-DAD-ESI-MS analysis on the extracts from axillary proliferation shoots (AP shoots) showed significant production of caffeic acid derivatives while leaf callus and LR shoots, accumulated mainly alkamides. These results showed that the proper choice of the procedures for in vitro multiplication allowed us to obtain plant biomass able to produce the active compounds typical of E. angustifolia plants.
2009-06-11
Article
PeerReviewed
application/pdf
it
http://eprints.adm.unipi.it/646/1/Echinacea_SH.pdf
Lucchesini, Mariella and Bertoli, Alessandra and Mensuali-Sodi, Anna and Pistelli, Luisa (2009) Establishment of in vitro tissue cultures from Echinacea angustifolia D.C. adult plants for the production of phytochemical compounds. Scientia Horticulturae, 122/20 (3). pp. 484-490. ISSN 0304-4238
http://www.sciencedirect.com/science/journal/03044238
doi:10.1016/j.scienta.2009.06.011
oai:eprints.adm.unipi.it:694
2010-12-20T10:47:44Z
7374617475733D707562
7375626A656374733D417265613033:4348494D2F3035
74797065733D61727469636C65
http://eprints.adm.unipi.it/694/
Internal structure and linear viscoelastic properties of EVA/asphalt nanocomposites
Sureshkumar, Markanday
Filippi, Sara
Polacco, Giovanni
Kazatchkov, Igor
Stastna, Jiri
Zanzotto, Ludovit
CHIM/05 - Scienza e tecnologia dei materiali polimerici
The effect of the addition of two different organoclays as a third component in polymer modified asphalts has been investigated. Ternary mixtures were prepared by adding clay and poly(ethylene-co-vinylacetate) to the asphalt, either separately, or in the form of a premixed master batch. The performed characterizations allowed the determination of how the two methods of mixing influence the interactions between asphalt and polymer and therefore the final rheological properties. In particular, it was shown that the clay had a compatibilizing effect on asphalt and polymer and that a high compatibility between clay and polymer led to a better dispersion of the polymer in the asphalt, thus influencing the final rheological properties of the studied systems.
2010
Article
PeerReviewed
application/pdf
it
http://eprints.adm.unipi.it/694/1/Markanday.pdf
Sureshkumar, Markanday and Filippi, Sara and Polacco, Giovanni and Kazatchkov, Igor and Stastna, Jiri and Zanzotto, Ludovit (2010) Internal structure and linear viscoelastic properties of EVA/asphalt nanocomposites. European Polymer Journal, 46/201 (4). pp. 621-633. ISSN 0014-3057
http://www.sciencedirect.com/science/journal/00143057
doi:10.1016/j.eurpolymj.2009.12.024