Giorgi, Mario (2008) Pharmacokinetic differences of tramadol in several animal species and human beings. Journal of veterinary resarch, 63/200 (Specia). pp. 1-4. ISSN 1022-646X
SUMMARY: Tramadol is an opioid centrally acting analgesic used in the two last decades to trait pain in humans. This review takes into account the PK/PD data in different tramadol formulations administered to humans. Since T has been recently suggest as potential molecule for long term therapy in chronic pain in animals, an evaluation of its PK/PD data in several animal species is also reported.
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